Demolition of Imperial College Medical School building to make way for 16-storey scheme

HOK has submitted plans for a huge life sciences scheme next to St Mary’s Hospital in Paddington.

Designed for developers Cohort Limited and Bartlet Asset Management, the 16-storey scheme would accommodate more than 1,800 clinicians across 48,000sq m of floorspace.

It would be built on Praed Road on the site of the Imperial College Medical School building, which has been vacant since 2024 and has been deemed unsuitable for reuse.

Cohort said demolition of the existing building was “not a decision taken lightly” but would offer the opportunity to create a “sustainable, inclusive building that supports health innovation for decades to come”.

Called Paddington Hub, the project is being developer under a collaboration agreement with the neighbouring St Mary’s Hospital with construction scheduled to begin next year and complete in 2029.

HOK design principal David Weatherhead said the scheme would provide “much-needed specialist space for clinical life sciences”.

Bartlet Asset Management director David Miller added: “Paddington Hub represents a significant investment in Paddington’s future and a once-in-a-generation opportunity to create a world-class clinical life sciences hub next to St Mary’s Hospital.

“It will drive economic growth, support new jobs and strengthen the UK’s health innovation sector. By bringing researchers, clinicians and patients together, we can accelerate new treatments, improve outcomes and create meaningful opportunities for local people.”

HOK is also acting as landscape architect on the project with others on the team including planning consultant DP9, structural engineer AKTII and energy and transport consultant Ramboll.

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